Wednesday, 15 June 2016

DAY 15: Renal / Kidney Involvement, Scleroderma Awareness Month 2016

DAY 15: Renal / Kidney Involvement, Scleroderma Awareness Month 2016 
Scleroderma can affect all parts of the body, and it is important to note that not every scleroderma patient will develop kidney related symptoms. 

Renal crisis occurs in 5% of patients, usually with the diffuse form, and usually, within the first few years of symptom manifestation. 

A positive Anti-RNA-polymerase III antibody test confirms kidney susceptibility, along with the symptoms listed in the image. A renal biopsy can also be carried out to confirm disease activity, if any, in the kidney. 

Not all those with a positive Anti-RNA-polymerase III antibody blood test result will go on to develop renal crisis.  

Severe renal crisis used to be the main cause of death in scleroderma patients. This has now been super-ceded by lung fibrotic involvement. 

The availability of angiotensin-converting enzyme inhibitors (ACEi) being used for prevention and treatment, and in some instances, in combination with other types of antihypertensive drugs, has improved the renal crisis patient outlook in this respect. 

Dialysis is also used as a treatment, with long term dialysis leading to a possible renal transplant. 

For more information on the UK Scleroderma Study Group renal management guidelines click  here and

This article was originally published here  in my Column with Scleroderma News. 

To read my articles:
The importance of an early diagnosis click here 
the role of medical research click here
the importance of expert specialist centres click here
diet and nutrition click here
taking part in research trials click here
the UK guidelines for management and treatment of Scleroderma click here
my skin is cured from scleroderma click here 
BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs, Raynaud's, Scleroderma, Rare Disease click here  

EULAR guidelines for treatment of systemic sclerosis scleroderma, click here  

Please DONATE to help fund medical research at the Scleroderma Unit at The Royal Free hospital where 100% of your donation will be used to fund vital medical research. Thank You.
May 2017 total
Living the dream, scleroderma style, hoping for a cure
#SclerodermaFreeWorld #RaynaudsFreeWorld
29th June World Scleroderma Day. Read more here   
Scleroderma Awareness flashback 2016. Read more here  
Scleroderma Awareness 2016 Campaign Index Click here  
Follow Raynauds Scleroderma Awareness Global Patients Facebook Page for latest updates 
To view the Facebook page Scleroderma Awareness Month 2016 campaign images Click  here
To view Facebook page Photo Album ‘Wellbeing Side to living with Raynaud’s and Scleroderma’ Click  here 

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